You may have access to different export options including Google Drive and Microsoft OneDrive and citation management tools like RefWorks and EasyBib. Studies revealed 69.10 and 80.35% blood glucose-lowering effect of AIS in maltose and sucrose loaded diabetic rats in comparison with the diabetic control group. The fruits are small and hairy. (PDF) The effect of Acalypha indica L. roots - ResearchGate editor = "Kenny Lischer and Sugeng Supriadi and Rahman, {Siti Fauziyah} and Yudan Whulanza". -, Whiting DR, Guariguata L, Weil C, Shawj IDF. These plants will benefit from regular watering in the growing season but will not need much water in the cooler months, provided you dont let the soil dry out. This is to ensure that we give you the best experience possible. This output contributes to the following UN Sustainable Development Goals (SDGs). )Rk{BB@3h%8.5b2~UNendstream Extracts and chemical constituents of this plant possess useful pharmacological activities. https://doi.org/10.1007/s13399-020-01094-1, DOI: https://doi.org/10.1007/s13399-020-01094-1. An official website of the United States government. As an Amazon Associate we earn from qualifying purchases (at no extra cost to you). represented, 50,000 A number of biological constituents in good yield and some have been shown to possess useful biological actions belonging mainly to tannins, flavonoids, cyanogenic glucoside (acalyphin), pyranoquinolinone alkaloid (flindersin). [13] Chopra RN, S.L. [14] Nadakarni K.M, A.M. Nadakarni. Each individual flower on its own is rather insignificant but in the long, pendulous inflorescences this plant is so popular for, the effect is striking. eCollection 2020. In our previous in-vitro investigation, methanolic extract of A. indica stems (AIS) proved to be an effective a-glucosidase inhibitor, antioxidant, and well tolerated in acute and subchronic toxicity studies in albino wistar rats. +|!C The results indicated that the ethanol leaf extract in the dose levels of 500 and 750mg/kg inhibited the Viper russelli venom induced lethality, haemorrhage, necrotizing and mast cell degranulation in rats and cardiotoxic, neurotoxic effects in isolated frog tissue in dose dependent manner. (1982) Acalyphin, A cyanogenic glucoside from Acalypha indica. Hypoglycemic effect of Padina arborescens extract in streptozotocin-induced Diabetic Mice. AI administration yielded a decrease of TNF-a in both the kidneys (0.95 0.76 pg/mg in the treatment group vs. 1.37 0.41 pg/mg in the negative control) and hearts (15.43 pg/mg 2.33 in the treatment group vs. 16.50 1.33 pg/mg in the negative control), of aged SD rats, albeit insignificantly. Food Hydrocoll 28(2):344352, Shaviklo AR, Rafipour F (2014) Consumer-based development and optimization of fish strudel using D-optimal mixture design. <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Although acalyphas are considered low-maintenance plants, they are fast-growing, and youll probably want to prune these plants to achieve a denser growth form. 9k;D(!P 4uc^A2|!c =fn9DA;Th50!J.k}ZZ8%,W6L"Fau{16@f?Z6-[rAVx>0b[E.~)!g~z@- Further, four known kaempferol glycosides such as biorobin, nicotiflorin, clitorin and mauritianin have been isolated from the dried methanol extract of freeze-dried flowers and leaves of Acalypha indica [10]. th Mar-2012 Revised: 30th Mar-2012 Accepted: 02 April True to their tropical nature, acalypha plants like to be kept in warm and humid conditions. Royal Botanic Gardens, Kew, UK. The site is secure. 101:465-70. FOIA 2017 May 5;203:260-278. doi: 10.1016/j.jep.2017.03.035. 1:5-6. Learn tips for creating your most beautiful home and garden ever. sharing sensitive information, make sure youre on a federal Green soap formulation: an insight into the optimization of Center for Disease Control. [25] Perumal Samy R, S. Ignacimuthu, D. Patric Raja. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf, NCI CPTC Antibody Characterization Program. abstract = "Non-communicable diseases, such as cardiovascular diseases or kidney dysfunctions, tend to have expensive and unavailable treatments. As, the acute hyperglycemia at postprandial period has more triggering effect on oxidative stress, study was also aimed to evaluate the antioxidant potential of AIS on STZ-induced Albino-Wistar rats. 48 Sprague Dawley rats aged 7 weeks, weighing 150-200g were randomly divided into four groups, 6 animals per gender. Most acalypha species can withstand fairly aggressive pruning (up to 25 percent of the plant's overall foliage) and still thrive. Your biggest challenge, once you meet its basic requirements, will likely be acalypha's fast-growing nature and tendency toward legginess. Kumar. Acalypha indica Vell. 2016 Apr 2;181:118-35. doi: 10.1016/j.jep.2016.01.036. !Nd"U_ezDPMUr>Z+4!EHSk 2014 Apr;10(Suppl 2):S207-13. Tiwari AK, Rao JM. to investigate effect of AIS in controling PPHG after carbohydrate loading. Careers. American Crystallographic Association, Inc. AVS: Science and Technology of Materials, Interfaces and Processing, https://doi.org/10.1016/S1499-2671(13)00108-1, https://doi.org/10.1371/journal.pone.0179186, https://doi.org/10.1152/physrev.00019.2009, https://doi.org/10.1136/postgradmedj-2014-133200, https://doi.org/10.1080/13880209.2016.1268635, https://doi.org/10.1016/j.jfda.2013.08.001, A review of the motivation theories in learning, What is big data? Indonesia is home to diverse sorts of vegetations as an agricultural power, such as Acalypha indica L. (AI). The leaves have crenate-serrate margin. wilkesiana: Copperleafhttps://edis.ifas.ufl.edu/pdffiles/FP/FP00600.pdf, (2) Gilman, E. F. Klein, R. & Hansen, G. Acalypha hispida: Chenille Plant https://edis.ifas.ufl.edu/pdffiles/FP/FP00400.pdf. Four successive solvent extracts such as chloroform, ethanol, petroleum ether and aqueous of the whole plant of Acalypha indica are tested for post-coital antifertility activity in female albino rats. J Ethnopharmacol. The plant is most vulnerable to common household pests like mealybugs and aphids, especially if nearby houseplants are infected. 74:1003-006. Acalypha indica commonly known as Indian copper leaf is used in traditional medicinal system to treat various diseases. The aqueous extracts of Tridax procumbens, Cleome viscosa, Acalypha indica and Boerhaavia erecta at two different weights of residues, 30 and 40mg were tested for antibacterial activities by the filter paper disc diffusion method. - 159.89.202.53. endobj Type 2 diabetes mellitus is a metabolic disorder that is characterized by hyperglycemia, insulin resistance, inadequate insulin secretion, and excessive glucagon secretion. Phyto-pharmacology of Acalypha indica: A Review, Dineshkumar, B; Vigneshkumar, P; Bhuvaneshwaran, S P; Mitra, Analava. The rats were then terminated after 28 days, and the major organs, kidneys, and hearts were examined using ELISA to look for TNF-a concentration. 2021;12(1):53. doi: 10.1186/s40543-021-00304-3. United Kingdom 2: 2-636. J Ethnopharmacol. 5 0 obj The chenille plant, on the other hand, produces very showy and interesting crimson flowers. The important biological activities and phytochemistry of CSIR. The solution wasapplied by hand pump sprayer to the surface of the approximately0.5 m3of water contained in each tank until a concentration of approx.200 ppm was achieved. stream Phytochemical Profile, Free Radical Scavenging and Anti-Inflammatory Properties of. Selangor, Malaysia, pp: 117, Thirunavukkarasu A, Nithya R (2011) Response surface optimization of critical extraction parameters for anthocyanin from Solanummelongena. Treatment of fatty pancreas: Acalypha indica Linn. extract Sahukari R, Punabaka J, Bhasha S, Ganjikunta VS, Kondeti Ramudu S, Kesireddy SR, Ye W, Korivi M. Molecules. He has always had a keen interest in the natural world and is actively involved in the study and protection of wild flora, particularly on the 400 hectare property where he lives. The plant is bitter to taste. In addition base of the leaf is wedge shaped or cuneate. Data collected were analyzed using Saphiro-Wilk test and one-way ANOVA. Start by housing your plant in a typically humid room in your house, like the kitchen or bathroom. Care should be taken not over-plant this species though because it really does have a bold look, wherever it is planted. Accessed 26 July 2020, Sharma B (2000) Industrial Chemistry (Including Chemical Engineering). indica Acalypha somalensis Pax Acalypha somalium Mll.Arg. WebAcalypha indica is a herb that grows throughout the tropical regions of the world. Many pharmacological studies of Acalypha indica have been demonstrated for their antioxidant, antimicrobial, anti-inflammatory, anti-diabetic, wound healing effect, anti-venom and anti-fertility activities, supporting its traditional uses. J Ethnopharmacol. government site. Further research in phytochemicals development from Acalypha indica will help to analayse therapeutic efficacy of products. Bethesda, MD 20894, Web Policies Cats were individually tested against each scent in a closed empty pre-acclimatised enclosure. '{tp: Would you like email updates of new search results? phrase ability, 13+ official website and that any information you provide is encrypted Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Hepatoprotective activity of AIS is evaluated in diabetic rats by treating them at the dosages 300-600 mg/kg b.w. New Delhi. Antiaging effects of Acalypha indica L. extract These showy broadleaf evergreens are native to the south pacific islands and Southeast Asia where they grow in warm, tropical, and humid habitats. Longer documents can take a while to translate. The paw volume was measured using a plethysmometer at 0-4 hours after injection. 6 0 obj After four weeks of treatment, rats were terminated and laboratory test was performed to see plasma insulin level using enzyme-linked immunosorbent assay. These plants can be grown in partial shade but unfortunately, they wont flower as well or develop the beautiful Rather than keep you waiting, we have only translated the first few paragraphs. and transmitted securely. (2005) Isolation and identification study of antimicrobial property of a bioactive compound in an Indian medicinal plant Acalypha indica (Indian-nettle), World J Microb Biot. Grow your acalypha bush in full sun for the best results. doi: 10.4103/0973-1296.133211. (2004) Acaricidal property of kuppaimeni (Acalypha indica) against natural Psoroptes cuniculi infestation in broiler rabbits, Indian J Anim Sci. Phytochem. If you log in through your library or institution you might have access to this article in multiple languages. Occasionally we offer vouchers or set up unique usernames and passwords for our users. A relatively short time of treatment in this study could be attributed to the insignificant decrease in kidney and cardiac tissue. GC-MS analysis of same extract revealed J Environ Biotechnol Res 8(2):1421, Rajarathinam N, Arunachalam T, Raja S, Selvasembian R (2020) Fenalan Yellow G adsorption using surface-functionalized green nanoceria: an insight into mechanism and statistical modelling. Acalypha indica extract was shown to augment the process of dermal wound healing by its ability to increase collagen synthesis through up-regulation of key players in Conclusion: Data collected were analyzed using Saphiro-Wilk test and one-way ANOVA. Rats were divided into four groups, the negative control (placebo), positive control using 6 IU vitamin E, treatment group using 250 mg/kg of body weight (mg/kg BW) AI extract, and control using young rats. t&ITiw|5cd |~6m(B=|?V Antiaging effects of Acalypha indica L. extract administration on tumor necrosis factor-a (TNF-a) protein level in major organs of aged Sprague-Dawley rats. PubMedGoogle Scholar. series = "AIP Conference Proceedings". The links between ethnomedicinal practices and scientific studies have been discussed with a fair justification. The hexane, chloroform, acetone and methanol extracts of fresh, dried and powdered samples of leaf, stem and roots of Acalypha indica were prepared by soxhlet apparatus. [22] Singh DAP, M. Raman, V. Saradha, P. Jayabharathi, V.R.S. Acalypha indica National Library of Medicine bI8VEk0:s\#hPB]TlXk`@ If you notice a sign of infestation, isolate the troubled plant immediately and treat it with a mild insecticide or horticultural oil like neem oil. Several A. indica extracts indicated antibacterial activities Additionally, the more organically rich your soil blend is, the faster (and fuller) your acalypha plant will grow. Please log in through your library or institution to check if you have access. official website and that any information you provide is encrypted The Acalypha indica plant is reported to have some of the therapeutic properties which are used in Siddha and Ayurveda as medicines. N2 - Non-communicable diseases, such as cardiovascular diseases or kidney dysfunctions, tend to have expensive and unavailable treatments. The https:// ensures that you are connecting to the Pharm Biol. Saudi J Biol Sci. 21:101-05. The multicolored leaves of the copperleaf plant grow in combinations of red, pink, copper, orange, yellow, white, green, and purple. This feature may be available for free if you log in through your library or institution. One such measure is the administration of antioxidants to counter the increasing inflammatory markers, such as TNF-a, in the pathogenesis of chronic non-communicable diseases. Yes and no. The male flowers are minute and crowded distally with 8 stamens. [21] Mohana Vamsi N, M. Venkata Sunil Kumar, N. Kodandaram, Y. Padmanabha Reddy. (2007) Antioxidant capacity of some edible and wound healing plants in Oman, Food Chem. The leaves of both species have serrated margins. It is used in case of acrid, diuretic, cathartic, expectorant, ernetic, anodyne, hypnotic, gastrointestinal irritation, laxative, bronchitis. However, the usage of synthetic antioxidants chronically may incur side effects and expensive. Fronczek, A. Nahrstedt. Arunachalam Thirunavukkarasu. Recent Updates on Phytoconstituent Alpha-Glucosidase Inhibitors: An Approach towards the Treatment of Type Two Diabetes. Biomass Conv. The rats were then terminated after 28 days, and the major organs, kidneys, and hearts were examined using ELISA to look for TNF-a concentration. f]j`5J\0+B!!]>a- u+}~@oQI9h=DJ@n[ ed5 xJ$#(*Xv5'mq%)o2%[?aNZtU:F[B%ax#vZ3bDl6o3;`@?G@5" b8xNU "-)7y"dSM4wF]Xe(^l>;NN^Be!QAY(`*|o1x:P%& Epub 2022 Jul 22. The pharmacological studies conducted on Acalypha indica indicate the immense potential of this plant in the treatment of conditions such as wounds, malaria, coughs, inflammatory, diabetes etc. Acalypha indica Further, this formulation was supplemented with Acalypha indica extract to prepare the green soap, and its antifungal activity was determined using the agar dilution method. Revisiting "Vegetables" to combat modern epidemic of imbalanced glucose homeostasis. (2004) Neutralization potential of Viper russelli russelli (Russell's viper) venom by ethanol leaf extract of Acalypha indica; J Ethnopharmacol. AI administration yielded a decrease of TNF-a in both the kidneys (0.95 0.76 pg/mg in the treatment group vs. 1.37 0.41 pg/mg in the negative control) and hearts (15.43 pg/mg 2.33 in the treatment group vs. 16.50 1.33 pg/mg in the negative control), of aged SD rats, albeit insignificantly. [24] Gangadevi V, S. Sethumeenal, S. Yogeswari, G. Rani. Acalypha fimbriata Baill. Biswas, S. Dev, M.M. AI has been used empirically by cultures across the globe and is found to have antioxidant properties. For best results, take a cutting in the spring, when new growth emerges on the plant. If you're still struggling to maintain a humid enough environment for your acalypha plant, you can always invest in a small space humidifier to keep near it. The female flowers are larger than the male flowers and are scaterred in arrangement. Acalypha indica L. | Species - India Biodiversity Portal It can grow up to 75cm in height [6, 7]. If you can't login to CAB Direct, it's likely that your library doesn't have a subscription. (1). 7:89-91. Acalyphas have simple, alternately arranged leaves that are 4 to 8 inches (10 to 20 cm) long and heart-shaped. This smaller species grows to just 18 inches (45 cm) tall and produces beautiful red flower spikes up to 3 inches (7.5 cm) long. Acalypha plants are definitely bright-light lovers. Prolonged use of metformin can cause mild and serious side effects. 8600 Rockville Pike Different pharmacological experiments in both in vitro and in vivo have been carried out and also identified the medicinally important phyto-constitutents. A consensual definition and a review of key research topics, Uric acid and glucose level in high fructose high cholesterol induced Sprague-Dawley rats after therapy with Acalypha indica Linn. Acalypha plants that are dry are more prone to leaf-drop and pests, as well as general decline. One of the alternative herbal remedies used to treat Type 2 diabetes mellitus is Acalypha indica Linn (AI). Acalypha indica, is an important Indian medicinal plant and widely used in Ayurveda and siddha for management of various diseases. Looking for more documents like this one? This species makes an excellent house plant or container plant, especially if grown in hanging pots. The findings exhibit that The combination of metformin and AI extract significantly decreased the insulin resistance index compared with the negative control (p=0,034).
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